Scientists develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer
Scientists developed a bifunctional therapeutic strategy by transforming living tumor cells into a therapeutic. Shah’s team engineered living tumor cells using the gene editing tool CRISPR-Cas9 and repurposed them to release tumor cell killing agent. In addition, the engineered tumor cells were designed to express factors that would make them easy for the immune system to spot, tag and remember, priming the immune system for a long-term anti-tumor response. The team tested their repurposed CRISPR-enhanced and reverse-engineered therapeutic tumor cells (ThTC) in different mice strains including the one that bore bone marrow, liver and thymus cells derived from humans, mimicking the human immune microenvironment...
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Electronic Bridge allows Rapid Energy Sharing between Semiconductors

Artistic depiction of electron transfer driven by an ultrashort laser pulse, across an interface between two atomically-thin materials.
Artistic depiction of electron transfer driven by an ultrashort laser pulse, across an interface between two atomically-thin materials. This transfer is facilitated by an interlayer ‘bridge’ state that electrons are able to access due to lattice vibrations in both materials. (Credit: Gregory M. Stewart/SLAC)

As semiconductor devices become ever smaller, researchers are exploring two-dimensional (2D) materials for potential applications in transistors and optoelectronics. Controlling the flow of electricity and heat through these materials is key to their functionality, but first we need to understand the details of those behaviors at atomic scales.

Now, researchers have discovered that electrons play a surprising role in how energy is transferred between layers of 2D semiconductor m...

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Microwave Imaging of Quasi-Periodic Pulsations at Flare Current Sheet

 Microwave emissions from the flare. The upper group is from flaring loops, and the lower group extends along reconnection current sheet. The background is an EUV image at 211 A. The gold curve represents the temporal variation curve of current sheet source at 8.4 GHz.

Quasi-periodic pulsations (QPPs; also known as quasi-periodic oscillations, i.e., QPOs) are electromagnetic emission phenomena that vary quasi-periodically with time. They appear in celestial transient events with different temporal/spatial scales, such as stellar flares, gamma ray bursts and fast radio bursts.

The sun, an ordinary star closest to us, is a place where flares with QPPs appear frequently...

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Strengthening Electron-triggered Light Emission

Decorative image resembling triangular prism and colorful lights.
Caption: Researchers have found a way to create much stronger interactions between photons and electrons, in the process producing a hundredfold increase in the emission of light from a phenomenon called Smith-Purcell radiation.
Credits:Courtesy of the researchers

A new method can produce a hundredfold increase in light emissions from a type of electron-photon coupling, which is key to electron microscopes and other technologies.

Researchers have found a way to create much stronger interactions between photons and electrons, in the process producing a hundredfold increase in the emission of light from a phenomenon called Smith-Purcell radiation. The finding has potential implications for both commercial applications and fundamental scientific research.

The way electrons interact w...

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