Immunotherapy Eliminates Disease-causing Cells in Mice with MS-like Disease

Successful cancer treatment approach extended to autoimmune disease. Researchers have shown that the cancer therapy known as CAR-T can be applied to multiple sclerosis (MS), an autoimmune disease of the nervous system. The findings extend the powerful tool of immunotherapy to autoimmune diseases, a class of diseases that are often debilitating and difficult to treat.

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

Now, studying mice with an autoimmune disease similar to multiple sclerosis (MS), researchers at Washington University School of Medicine in St...

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Peekaboo! Tiny, Hidden Galaxy provides a Peek into the Past

NASA’s Hubble Space Telescope captured a detailed image of the tiny galaxy HIPASS J1131–31, nicknamed the “Peekaboo Galaxy,” despite its proximity to a bright foreground star. In addition to Hubble imagery, astronomers used the South African Large Telescope to collect detailed spectroscopic data on the galaxy’s stars, which show it to be one of the least chemically enriched galaxies ever discovered in the local universe.
Credits: NASA, ESA, and Igor Karachentsev (SAO RAS); Image Processing: Alyssa Pagan (STScI)

Peeking out from behind the glare of a bright foreground star, astronomers have uncovered the most extraordinary example yet of a nearby galaxy with characteristics that are more like galaxies in the distant, early universe...

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Off-Patent Liver Disease Drug could Prevent COVID-19 Infection and Protect against Future Variants, researchers find

Close up of bile duct/liver organoid infected with SARS-CoV-2 – red indicates the virus. (Credit: Teresa Brevini)

Unique experiments involved ‘mini-organs’, animal research, donated human organs, volunteers and patients. Cambridge scientists have identified an off-patent drug that can be repurposed to prevent COVID-19 — and may be capable of protecting against future variants of the virus — in research involving a unique mix of ‘mini-organs’, donor organs, animal studies and patients.

The research, published today in Nature, showed that an existing drug used to treat a type of liver disease is able to ‘lock’ the doorway by which SARS-CoV-2 enters our cells, a receptor on the cell surface known as ACE2...

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New Quantum Dots study uncovers Implications for Biological Imaging

CdZnSe/CdZnS quantum dots (QDs) have a complex internal structure that extends the lifetime. (A) TEM analyses reveal a zinc selenide-rich core interior and a cadmium sulfide shell exterior. (B) Time resolved emission reveals lifetime tunability by simple alterations to the QD structure. The lifetimes can be 10-times greater compared with similar materials.

Researchers report the synthesis of semiconductor ‘giant’ core-shell quantum dots with record-breaking emissive lifetimes. In addition, the lifetimes can be tuned by making a simple alteration to the material’s internal structure.

A new study involving researchers at the University of Illinois Chicago achieved a milestone in the synthesis of multifunctional photonic nanomaterials.

The group, which included collaborators from Pr...

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