Why Late-Night Eating leads to Weight Gain, Diabetes

The science behind the study is underpinned by research done at Northwestern more than 20 years ago that found a relationship between the internal molecular clock and body weight, obesity and metabolism in animals.

Health benefits come from eating during the daytime, demonstrating a potential link to energy release. Northwestern Medicine scientists have uncovered the mechanism behind why eating late at night is linked to weight gain and diabetes.

The connection between eating time, sleep and obesity is well-known but poorly understood, with research showing that over-nutrition can disrupt circadian rhythms and change fat tissue.

New Northwestern research has shown for the first time that energy release may be the molecular mechanism through which our internal clocks control energ...

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Improving Light Absorption in Perovskite/Si Tandem Solar Cells

1. (a) A schematic of the PDMS layer containing SGA phosphors and SiO2 nanoparticles, (b) photographs of the PDMS layer with SGA phosphors and SiO2 nanoparticles under ambient light and UV light (λ = 365 nm), (c) a schematic of perovskite/Si tandem solar cell with the PDMS layer containing SGA phosphors and SiO2 nanoparticles, and (d) a cross-sectional SEM image of the perovskite–Si solar cell.

A research team, affiliated with UNIST has succeeded in achieving a power conversion efficiency (PEC) of 23.50% in a perovskite-silicon tandem solar cell built with a special textured anti-reflective coating (ARC) polymeric film. According to the research team, the PCE of the device with the ARC film was sustained for 120 hours, maintaining 91% of its initial value.

This breakthrough has b...

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Why NASA is trying to Crash Land on Mars

This prototype base for SHIELD – a collapsible Mars lander that would enable a spacecraft to intentionally crash land on the Red Planet, absorbing the impact – was tested in a drop tower at JPL on Aug. 12 to replicate the impact it would encounter landing on Mars. Credit: NASA/JPL-Caltech

NASA has successfully touched down on Mars nine times, relying on cutting-edge parachutes, massive airbags, and jetpacks to set spacecraft safely on the surface. Now engineers are testing whether or not the easiest way to get to the Martian surface is to crash.

Rather than slow a spacecraft’s high-speed descent, an experimental lander design called SHIELD (Simplified High Impact Energy Landing Device) would use an accordion-like, collapsible base that acts like the crumple zone of a car and abs...

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Manipulating Stress Response in Cells could help Slow Down Aging

Glucose extends lifespan in aged worms independently of the DAF-16
(FOXO). Differentially regulated genes downstream of the insulin/insulin-like
growth factor signalling (IIS) (a), daf-16 (b), hsf-1 independently (ind.) of heat shock
(HS) (c, d) in animals fed on the normal diet (ND) or high-glucose diet (HGD) from
5-day old (HGD-5). e Lifespan assays of daf-16(lof) animals fed on the ND or HGD-5
(ND, n = 502; HGD-5, n = 536 including biological replicates). f, g Representative
images of DAF-16::GFP localisation in 1- (D1) and 5-day old (D5) worms on 16 h ND,
HGD (filled circles) or 1 h heat shock (filled circles) at 37 °C (n = 60 for each condition including biological replicates). Scale bars represent 100 μm (f) and 25 μm
(g). Highlighted worms with dashed lines are WT animals...
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