Immune Surprise: Recently Evolved Alarm Molecule drives Inflammation

Cells expressing inflammatory cytokines stained green
Cells expressing inflammatory cytokines, stained green. Image: Martin Laboratory, Trinity College Dublin.

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite.

Their work has numerous potential impacts, especially in the context of understanding and responding to autoimmune disorders and inflammation.

While our immune system serves a very important function protecting us from infection and injury, when immune responses become too aggressive this can lead to damaging inflammation, which occurs in conditions such as rheumatoid arthritis and psoriasis...

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Researchers develop All-Optical Approach to Pumping Chip-Based Nanolasers

Caption: Researchers have developed a new all-optical method for driving multiple high density nanolaser arrays using light traveling down a single optical fiber. The optical driver creates programmable patterns of light via interference.
Image Credit: Myung-Ki Kim, Korea University

New technology could aid in meeting the ever-growing need to move more data faster. Researchers have developed a new all-optical method for driving multiple highly dense nanolaser arrays. The approach could enable chip-based optical communication links that process and move data faster than today’s electronic-based devices.

“The development of optical interconnects equipped with high-density nanolasers would improve information processing in the data centers that move information across the internet,” sai...

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Ancient Asteroid Grains provide insight into the Evolution of our Solar System

Image taken at E01 ePSIC of Ryugu serpentine and Fe oxide minerals. Credit: ePSIC/University of Leicester.
Image taken at E01 ePSIC of Ryugu serpentine and Fe oxide minerals. Credit: ePSIC/University of Leicester.

The UK’s national synchrotron facility, Diamond Light Source, was used by a large, international collaboration to study grains collected from a near-Earth asteroid to further our understanding of the evolution of our solar system.

Researchers from the University of Leicester brought a fragment of the Ryugu asteroid to Diamond’s Nanoprobe beamline I14 where a special technique called X-ray Absorption Near Edge Spectroscopy (XANES) was used to map out the chemical states of the elements within the asteroid material, to examine its composition in fine detail...

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Wearable Skin Patch Monitors Hemoglobin in Deep Tissues

The new, flexible, low form-factor wearable patch comfortably attaches to the skin, allowing for noninvasive long-term monitoring.
The new, flexible, low form-factor wearable patch comfortably attaches to the skin, allowing for noninvasive long-term monitoring. Photo by Xiaoxiang Gao for the Jacobs School of Engineering at UC San Diego.

A photoacoustic sensor could help clinicians diagnose tumors, organ malfunction and more. A team of engineers at the University of California San Diego has developed an electronic patch that can monitor biomolecules in deep tissues, including hemoglobin. This gives medical professionals unprecedented access to crucial information that could help spot life-threatening conditions such as malignant tumors, organ dysfunction, cerebral or gut hemorrhages and more.

“The amount and location of hemoglobin in the body provide critical information about blood perfusion or accumulation in ...

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