Molecular switch links early life stimulation to lasting memory changes

Researchers identify the molecular mechanisms linking early-life environments with memory
Mice raised in enriched environments show improved learning and memory driven by sustained activation of the transcription factor AP-1, the molecular ‘switch’ that converts early-life experiences into lasting changes in the brain. Credit: Instituto de Neurociencias UMH-CSIC

Researchers have identified a molecular mechanism that helps explain why growing up in a stimulating environment enhances memory. In contrast, a lack of stimulation can impair it. The team from the Institute for Neurosciences (IN), a joint research center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), was led by researcher Ángel Barco.

Their study, conducted in mice and published in Nature Communications, demonstrates that the environment during childhood and ado...

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Interstellar object covered in ‘icy volcanoes’ could rewrite our understanding of how comets formed

Interstellar object covered in
Nov. 19 image obtained by Pau Montplet from Breda (Girona) using a C6 telescope at f:7. Original image is in the lower right inset, while a false color 0.6º wide Larson-Sekanina filtered image at 9º shows 3I in negative to remark the antitail pointing to the subsolar point, and several jets getting out from the false nucleus. Two additional arrows mark wavy structures in the jets. Image resolution is 0.7 arcsec/pix. Credit: arXiv (2025). DOI: 10.48550/arxiv.2511.19112

Analysis of the second confirmed interstellar comet to visit our solar system suggests that the alien body could be covered in erupting icy, volcano-like structures called cryovolcanoes...

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Exercise slows tumor growth in mice by shifting glucose uptake to muscles

mice run wheel
Credit: Unsplash/CC0 Public Domain

It’s well known that exercise is good for health and helps to prevent serious diseases, like cancer and heart disease, along with simply making people feel better overall. However, the molecular mechanisms responsible for preventing cancer or slowing its progression are not well understood. But, a new study, published in the Proceedings of the National Academy of Sciences, reveals how exercise can increase glucose and oxygen uptake in the skeletal and cardiac muscles, instead of allowing it to “feed” tumors.

Reduced tumor growth in exercised mice
To study how exercise-induced metabolic changes affect tumor growth, the research team injected mice with breast cancer cells and fed some of the mice a high-fat diet (HFD), consisting of 60% calories from ...

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Engineers develop thin film to make AI chips faster and more energy efficient

UH engineers making AI faster, reducing power consumption
This is the two-dimensional thin film electric insulator designed in the University of Houston lab of Alamgir Karim to make AI faster and reduce power consumption. Credit: University of Houston

Addressing the staggering power and energy demands of artificial intelligence, engineers at the University of Houston have developed a revolutionary new thin-film material that promises to make AI devices significantly faster while dramatically cutting energy consumption.

The breakthrough, detailed in the journal ACS Nano, introduces a specialized two-dimensional (2D) thin film dielectric—or an electric insulator—designed to replace traditional, heat generating components in integrated circuit chips...

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