Norovirus and other ‘Stomach Viruses’ can Spread through Saliva

This microscopic view shows image of salivary gland acinar epithelial cells infected with rotavirus, a type of enteric virus, in a mouse.

A class of viruses known to cause severe diarrheal diseases – including the one famous for widespread outbreaks on cruise ships – can grow in the salivary glands of mice and spread through their saliva, scientists at the National Institutes of Health have discovered. The findings show that a new route of transmission exists for these common viruses, which afflict billions of people each year worldwide and can be deadly.

The transmission of these so-called enteric viruses through saliva suggests that coughing, talking, sneezing, sharing food and utensils, and even kissing all have the potential for spreading the viruses. The new findings still need to be confirmed in human studies.

The findings, which appear in the journal Nature, could lead to better ways to prevent, diagnos...

Read More

New Single-Mode Semiconductor Laser delivers Power with Scalability

Schematic of the Berkeley Surface Emitting Laser (BerkSEL)
Schematic of the Berkeley Surface Emitting Laser (BerkSEL) illustrating the pump beam (blue) and the lasing beam (red). The unconventional design of the semiconductor membrane synchronizes all unit-cells (or resonators) in phase so that they are all participating in the lasing mode. (Image courtesy of the Kanté group)

Berkeley engineers have created a new type of semiconductor laser that accomplishes an elusive goal in the field of optics: the ability to maintain a single mode of emitted light while maintaining the ability to scale up in size and power. It is an achievement that means size does not have to come at the expense of coherence, enabling lasers to be more powerful and to cover longer distances for many applications.

A research team led by Boubacar Kanté, Chenming Hu Asso...

Read More

Falling Stardust, Wobbly Jets explain Blinking Gamma Ray Bursts

New simulation also shows gamma ray bursts are 10 times rarer than previously thought. A Northwestern University-led team of astrophysicists has developed the first-ever full 3D simulation of an entire evolution of a jet formed by a collapsing star, or a “collapsar.”

Because these jets generate gamma ray bursts (GRBs) — the most energetic and luminous events in the universe since the Big Bang — the simulations have shed light on these peculiar, intense bursts of light. Their new findings include an explanation for the longstanding question of why GRBs are mysteriously punctuated by quiet moments — blinking between powerful emissions and an eerily quiet stillness. The new simulation also shows that GRBs are even rarer than previously thought.

The new study will be published on Ju...

Read More

Skin’s Protective Chains uncovered

Structures and nomenclature of human ceramide classes. A and B: Structures of LCBs (A) and FAs (B) in human ceramides. The abbreviations used in this study are shown in parentheses after each compound name, and those recommended by LIPID MAPS (https://www.lipidmaps.org) are shown below them, with each number corresponding to an n value of 1 or 15, as indicated in the figure. Two models have been proposed for how protein-bound ceramides bind to corneocyte envelope proteins

The skin’s top layer contains a diverse set of hundreds of lipid molecules called ceramides with varying chain lengths that play a vital role in its barrier function.

Ceramides are a type of lipid that are found in abundance in the top layer of the skin, called the stratum corneum...

Read More