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    Bacteria-based Biohybrid Microrobots on a Mission to one day Battle Cancer

    July 19, 2022, Categories  Health/Medical, Biology/Biotechnology

    Bacterial biohybrids carrying nanoliposomes (200 nm) and magnetic nanoparticles (100 nm). Nanoliposomes are loaded with chemotherapeutic DOX and photothermal agent ICG, and both cargoes are conjugated to E. coli bacteria (2 to 3 µm in length) via biotin-streptavidin interactions. Akolpoglu et al., Sci. Adv. 8, eabo6163 (2022).

    A team of scientists in the Physical Intelligence Department at the Max Planck Institute for Intelligent Systems have combined robotics with biology by equipping Ecoli bacteria with artificial components to construct biohybrid microrobots. First, the team attached several nanoliposomes to each bacterium. On their outer circle, these spherical-shaped carriers enclose a material (ICG, green particles) that melts when illuminated by near infrared light...

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    ‘Black Hole Police’ discover a Dormant Black Hole outside our Galaxy

    July 19, 2022, Categories  Astronomy/Space

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    A team of international experts, renowned for debunking several black hole discoveries, have found a stellar-mass black hole in the Large Magellanic Cloud, a neighbour galaxy to our own. “For the first time, our team got together to report on a black hole discovery, instead of rejecting one,” says study leader Tomer Shenar. Moreover, they found that the star that gave rise to the black hole vanished without any sign of a powerful explosion. The discovery was made thanks to six years of observations obtained with the European Southern Observatory’s (ESO’s) Very Large Telescope (VLT).

    A team of international experts, renowned for debunking several black hole discoveries, have found a stellar-mass black hole in the Large Magellanic Cloud, a neighbour galaxy to our own...

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    Scientists Reveal New Function of Enzyme ADAR1 Linking it to Age-Related Diseases via a Role Independent of RNA-editing during Aging

    July 19, 2022, Categories  Health/Medical, Biology/Biotechnology

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    ADAR1 regulates SIRT1 expression.

    Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders. In a research paper published today in Nature Cell Biology, Rugang Zhang, Ph.D., deputy director of the Ellen and Ronald Caplan Cancer Center, Christopher M. Davis Endowed Professor, and program leader of the Immunology, Microenvironment & Metastasis Program, at The Wistar Institute, and his team revealed a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence and its potential implications in tissue aging.

    “Understanding the basic mechanism underlying tissue aging is challenging and cellular senescence offers an...

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    Researchers Learn to Control Electron Spin at Room Temperature to make Devices more Efficient and Faster

    July 19, 2022, Categories  Physics, Technology/Electronics

    In a Rashba-Dresselhaus spin transistor, the spin of electrons could be disrupted by spin-phonon coupling or non-ideal internal magnetic field distribution. Credit: Jian Shi

    Electron spin, rather than charge, holds the key. As our devices become smaller, faster, more energy efficient, and capable of holding larger amounts of data, spintronics may continue that trajectory. Whereas electronics is based on the flow of electrons, spintronics is based on the spin of electrons.

    An electron has a spin degree of freedom, meaning that it not only holds a charge but also acts like a little magnet. In spintronics, a key task is to use an electric field to control electron spin and rotate the north pole of the magnet in any given direction.

    The spintronic field effect transistor harnesses th...

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