Closing in on a universal vaccine: Nasal spray protects mice from respiratory viruses, bacteria and allergens

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Stanford Medicine researchers have developed an intranasal vaccine that protects mice against respiratory viruses, bacteria and allergens.
Chinamon/Adobe Stock

In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail—and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators have taken an astonishing step forward in that quest, surprising even themselves.

In a new study in mice, they have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens. The vaccine is delivered intranasally—such as through a nasal spray—and provides broad protection in the lungs for several months.

In the study, published in Sci...

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Largest ever radio sky survey maps the universe in unprecedented detail

An international collaboration using the Low Frequency Array (LOFAR) has published an exceptionally detailed radio sky map, revealing 13.7 million cosmic sources and delivering the most complete census yet of actively growing supermassive black holes. It showcases an extraordinary variety of systems powered by these black holes, whose radio emission can extend for millions of light-years.

The newly released LOFAR Two-meter Sky Survey (LoTSS-DR3) marks a major milestone in radio astronomy and international scientific collaboration. The results will be published in Astronomy & Astrophysics.

By observing the sky at low radio frequencies, the survey reveals a dramatically different view of the universe than that seen at optical wavelengths...

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Scientists find a mechanism showing how exercise protects the brain

Scientists find a mechanism for how exercise protects the brain
Credit: Cell (2026). DOI: 10.1016/j.cell.2026.01.024

Researchers at UC San Francisco have discovered a mechanism that could explain how exercise improves cognition by shoring up the brain’s protective barrier. With age, the network of blood vessels—called the blood–brain barrier—gets leaky, letting harmful compounds enter the brain. This causes inflammation, which is associated with cognitive decline and is seen in conditions like Alzheimer’s disease. The research is published in the journal Cell.

Six years ago, the team identified a brain-rejuvenating enzyme called GPLD1 that mice produced in their livers when they exercised. But they couldn’t understand how it worked, because it cannot get into the brain.

The new study answers that question...

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The Moon is still shrinking and it could trigger more moonquakes

A small mare ridge in Northeast Mare Imbrium taken by the Lunar Reconnaissance Orbiter Camera. Image Credit: NASA/GSFC/Arizona State University

The shrinking Moon is still cracking—and scientists just found where it might quake next. Researchers have created the first worldwide map and detailed study of small mare ridges (SMRs), subtle geological features that signal tectonic activity on the Moon. The findings, published in The Planetary Science Journal, come from scientists at the National Air and Space Museum’s Center for Earth and Planetary Studies and their collaborators.

For the first time, scientists show that these ridges are relatively young and spread widely across the lunar maria, the broad, dark plains visible from Earth...

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