Study finds Nanomedicine Targeting Lymph Nodes Key to Triple Negative Breast Cancer Treatment

Human metastatic breast cancer in the lymph nodes. National Cancer Institute – Visuals Online

Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer.

A study led by Duxin Sun, Ph.D., found that targeting the immune microenvironment in lymph nodes and tumors simultaneously led to long-term tumor remission in mice models of metastatic triple negative breast cancer. Further, using nanoparticles to deliver these immune-altering drugs increases treatment efficacy. These results appear in Science Translational Medicine.

Immunotherapy combined with chemotherapy has been long approved as standard treatment option for triple negative breast cancer but only shows a limited response in patients...

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New Transistors integrating High-k Perovskite Oxides and 2D Semiconductors

Over the past decades, electronics engineers and material scientists worldwide have been investigating the potential of various materials for fabricating transistors, devices that amplify or switch electrical signals in electronic devices. Two-dimensional (2D) semiconductors have been known to be particularly promising materials for fabricating the new electronic devices.

Despite their advantages, the use of these materials in electronics greatly depends on their integration with high-quality dielectrics, insulating materials or materials that are poor conductors of electrical current. These materials, however, can be difficult to deposit on 2D semiconductor substrates.

Researchers at Nanyang Technological University, Peking University, Tsinghua University, and the Beijing Acade...

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Chinese Rover finds evidence that Water was present on Mars more Recently than thought

A team of researchers at the Chinese Academy of Sciences, working with a colleague from the University of Copenhagen, has found evidence that water was present on Mars more recently than has been thought. In their paper published in the journal Science Advances, the group describes their analysis of data from China’s Zhurong rover and what it showed them about ice in hydrated minerals.

Prior research has suggested that parts of the Martian surface were covered with water up until approximately 3 billion years ago. The time since the water dried up on Mars is known as the Amazonia period. In this new effort, data from the Chinese rover Zhurong has shown the researchers evidence that water on Mars might have persisted longer than has been thought.

Rover Zhurong has been traveling ...

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Laser Bursts Drive Extremely Fast Logic Gates

Synchronized laser pulses (red and blue) generate a burst of real and virtual charge carriers in graphene that are absorbed by gold metal to produce a net current. “We clarified the role of virtual and real charge carriers in laser-induced currents, and that opened the way to the creation of ultrafast logic gates,” says Ignacio Franco, associate professor of chemistry and physics at Rochester. (University of Rochester illustration / Michael Osadciw)

Decisive step toward creating ultrafast computers. A long-standing quest for science and technology has been to develop electronics and information processing that operate near the fastest timescales allowed by the laws of nature.

A promising way to achieve this goal involves using laser light to guide the motion of electrons in matt...

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