Nanotechnology used to Destroy and Prevent Relapse of Solid Tumor Cancers

 B7 co-stimulation enhances the anti-PD1-based immunosuppression reversal.

As people across the globe look forward to longer life expectancies, malignant cancers continue to pose threats to human health. The exploration and development of immunotherapy aims to seek new breakthroughs for the treatment of solid tumours.

The successful establishment of anti-tumour immunity requires the activation, expansion and differentiation of antigen-specific lymphocytes. This process largely depends on specific interactions between various T cells and antigen-presenting cells (APCs) in the body. However, existing tumour vaccines, such as neoantigen vaccines and various vector vaccines, all rely on random interactions with APCs in the body...

Read More

Earth-Abundant Solar Pixels found to produce Hydrogen for Weeks

Multiple BiOI and BiOI-BiVO4 pixels on a device.
Multiple BiOI and BiOI-BiVO4 pixels on a device. Credit: Dr Virgil Andrei.

Devices made of readily available oxide and carbon-based materials can produce clean hydrogen from water over weeks — according to new research.

The findings, co-led by Dr Virgil Andrei, a Research Fellow at St John’s College, University of Cambridge, with academics at Imperial College London, could help overcome one of the key issues in solar fuel production, where current earth-abundant light-absorbing materials are limited through either their performance or stability.

Underexplored materials for light harvesting

Hydrogen fuel will play a critical role in the transition to full decarbonisation and reaching the UK’s goal of net-zero emissions by 2050...

Read More

Colossal Collisions linked to Solar System Science

Image of Abell 2146

A new study shows a deep connection between some of the largest, most energetic events in the universe and much smaller, weaker ones powered by our own Sun.

The results come from a long observation with NASA’s Chandra X-ray Observatory of Abell 2146, a pair of colliding galaxy clusters located about 2.8 billion light-years from Earth. The new study was led by Helen Russell from the School of Physics and Astronomy at the University of Nottingham.

Galaxy clusters contain hundreds of galaxies and huge amounts of hot gas and dark matter and are among the largest structures in the universe...

Read More

Targeted Micronutrition Ameliorates Allergy Symptoms

(c) 2019 galsand/Shutterstock

Study offers a new approach in the care of allergy sufferers. Micronutrient deficiencies can promote inflammation and render the immune system particularly sensitive to allergenic substances. In particular, iron deficiency signals danger to immune cells and leads to a more pronounced, exaggerated immune response. For the first time, scientists at the Messerli Research Institute of MedUni Vienna, Vetmeduni Vienna and the University of Vienna conducted a placebo-controlled trial and showed that targeted dietary measures can reduce the symptom burden in allergic reactions. The researchers are therefore treading a completely new path in the care of allergy sufferers. The study was recently published in The Journal of Allergy and Clinical Immunology: In Practice.

The background to the s...

Read More