RNA Binding Proteins help T cells pick their Weapons before Battle

Scientists at the Babraham Institute have shown that two RNA binding proteins hold the key to a stronger immune response to influenza in mice. Their findings, published today in Nature Communications, reveal that the absence of these proteins changes the potency of T cells that arise at the start on an infection. Further research could lead to implications for therapies that harness the immune system, and for vaccine design.

Researchers from the Turner lab focussed on the activity of the RNA binding proteins ZFP36 and ZFP36L1. By studying mice lacking these RNA binding proteins, the researchers were able to show that their absence in T cells during the initial phase of a viral infection leads to a superior cytotoxic immune response.

When the researchers infected mice with influe...

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Supernova Reveals Secrets to Astronomers

This schematic of Supernova 2014C shows the various ejecta and winds (red and purple) given off by the exploding star (left, yellow). The common-envelope disk (blue) surrounds both stars, the one exploding as a supernova and its binary partner (not shown). The boundary layer around the common-envelope disk is the source of the hydrogen the team detected. (credit: B. Thomas et al./UT Austin)  

An international group of astronomers led by Benjamin Thomas of The University of Texas at Austin has used observations from the Hobby-Eberly Telescope (HET) at the university’s McDonald Observatory to unlock a puzzling mystery about a stellar explosion discovered several years ago and evolving even now...

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How it works: The Protein that Stimulates Muscle Growth

In the gym, you are not just pumping iron, you are oxygenating muscle cells which keeps those muscles healthy, strong and growing in a process called hypertrophy.

Research findings may help identify drug targets for neuromuscular disorders. Using genetic approaches, researchers have demonstrated how a certain protein is involved in skeletal muscle growth. The findings open new avenues to develop drug targets for neuromuscular diseases and other pathological conditions.

In the gym, you are not just pumping iron, you are oxygenating muscle cells which keeps those muscles healthy, strong and growing — a process called hypertrophy, or an increase in muscle mass due to an increase in muscle cell size. Conversely, under the covers, lounging, your muscles may begin to atrophy, or shrink.

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Electronic Skin anticipates and perceives Touch from Different Directions for the First Time

Artificial electronic skin (e-skin): Highly integrated flexible microelectronic 3D sensorics perceive movement of fine hairs on artificial skin. (Image: AG Prof. Dr. Oliver G. Schmidt)

A research team from Chemnitz and Dresden has taken a major step forward in the development of sensitive electronic skin (e-skin) with integrated artificial hairs. E-skins are flexible electronic systems that try to mimic the sensitivity of their natural human skin counterparts. Applications range from skin replacement and medical sensors on the body to artificial skin for humanoid robots and androids. Tiny surface hairs can perceive and anticipate the slightest tactile sensation on human skin and even recognize the direction of touch...

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