Uncovered: Key to how Exercise Protects against Consequences of Ageing

Staining showing mitochondria within individual muscle fibres. Credit: Monash University

Monash University, Australia scientists have discovered an enzyme that is key to why exercise improves our health. Importantly this discovery has opened up the possibility of drugs to promote this enzyme’s activity, protecting against the consequences of aging on metabolic health, including type 2 diabetes.

The proportion of people worldwide over 60 years old will double in the next three decades and by 2031, more than six million Australians will be over 65 years old. The incidence of type 2 diabetes increases with age so this aging population will also result in an increased incidence of the disease globally.

One of the main reasons for the increased prevalence of type 2 diabetes with age i...

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Scientists Develop Biodegradable Printed Paper Batteries

Fabrication and characterizations of hydrogel cellulose paper (HCP). a) Schematic of original CP and HCP. b) Optical image of HCP (top) and original CP (bottom) with printed circuit patterns. c) One piece of HCP under mechanical deformation. SEM images of d) CP and e) HCP. f) Stress–strain curves of HCP and CP. g) The biodegradability tests of CP (left) and HCP (right) under moist soil. Yellow dash circles show outline of the samples. h) Photograph of a dry HCP (left) and a swollen HCP (right) with printed patterns. Blue dash squares with the same size of 30 mm × 30 mm show the boundaries of HCP. i) Galvanostatic plating/stripping curves of zinc symmetrical cells at a current density of 5 mA cm−2 and a cut-off capacity of 1 mAh cm−2. Credit: DOI: 10.1002/advs.202103894

Scienti...

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Size Doesn’t Matter: Rock Composition determines how deadly a Meteorite Impact is

The minerology of the rocks that a meteorite hits, rather than the size of the impact, determines how deadly an impact it will have. A new University of Liverpool study has found that the minerology of the rocks that a meteorite hits, rather than the size of the impact, determines how deadly an impact it will have.

The earth has been bombarded by meteorites throughout its long history. Meteorite impacts generate atmospheric dust and cover the Earth’s surface with debris and have long been considered as a trigger of mass extinctions through Earth’s history.

A multidisciplinary research team from the University of Liverpool and the Instituto Tecnológico y de Energías Renovables, Tenerife with expertise in palaeontology, asteroid stratigraphy, mineralogy, cloud microphysics and cli...

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For Children, Young Adults with Recurrent AML, Immunotherapy Shows Promise

GARA ELIZABETH PHOTOGRAPHYResearchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that pre-activated natural killer cells can help some children and young adults with recurrent AML and few other treatment options. Pictured is Weston Robinett, 3, a patient who received this investigational therapy at Siteman Kids at St. Louis Children’s Hospital and Washington University School of Medicine. He remains in remission more than two years after treatment.

Natural killer cells could help young patients with few treatment options. An immunotherapy harnessing the immune system’s “natural killer” cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return...

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