In the human brain, the hormone insulin also acts on the most important neurotransmitter for the reward system, dopamine. This was shown by researchers from the German Center for Diabetes Research (DZD) in Tübingen. Insulin lowers the dopamine level in a specific region of the brain (striatum *) that regulates reward processes and cognitive functions, among other things. This interaction can be an important driver of the brain’s regulation of glucose metabolism and eating behavior. The study has now been published in the Journal of Clinical Endocrinology & Metabolism.

Worldwide, more and more people are developing obesity and type 2 diabetes. Studies show that the brain plays an important role in causing these diseases...

Scientists at the University of Birmingham have succeeded in creating an experimental model of an elusive kind of fundamental particle called a skyrmion in a beam of light.

The breakthrough provides physicists with a real system demonstrating the behavior of skyrmions, first proposed 60 years ago by a University of Birmingham mathematical physicist, Professor Tony Skyrme.

Skyrme’s idea used the structure of spheres in 4-dimensional space to guarantee the indivisible nature of a skyrmion particle in 3 dimensions. 3D particle-like skyrmions are theorized to tell us about the early origins of the Universe, or about the physics of exotic materials or cold atoms...

Exotic laser-produced high-energy-density (HED) plasmas akin to those found in stars and nuclear explosions could provide insight into events throughout the universe. Physicists at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL) have discovered a new way to measure and understand these plasmas, among the most extreme states of matter ever produced on Earth. Improved understanding could provide benefits ranging from fine-tuning the high-density plasmas in inertial confinement fusion experiments to better understanding of processes throughout the universe.

A billion times denser

HED plasmas are a billion times denser...

Loss of this gene affects daily behavior, disrupting ~24-hour sleep-wake cycles. Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.

A recent Northwestern University discovery could help in understanding how this clock is linked to daily cycles. A team of neurobiologists has identified a new gene, called Tango10, that is critical for daily behavioral rhythms. This gene is involved in a molecular pathway by which the core circadian clock (the “gears”) controls the cellular output of the clock (the “hands”) to control daily sleep-wake cycles.

While the study was done using the fruit fl...