Research in Mice shows how Diet Alters Immune System Function through a Gut Microbe

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Research in mice demonstrates how diet alters a gut microbe molecule that, in turn, prompts immune cells to downregulate inflammation. The study elucidates molecular mechanism behind long-standing belief that diet, microbiota, and immunity influence one another in myriad ways. If affirmed in larger animals and humans, the findings could inform the design of small-molecule drugs that regulate immune response to treat inflammatory conditions.

The cliché “you are what you eat” has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

The work, conducte...

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New Holographic Camera sees the Unseen with High Precision

holographic camera
A setup of one of the prototypes in the laboratory

Device can see around corners and through scattering media like fog and human tissue. Northwestern University researchers have invented a new high-resolution camera that can see the unseen — including around corners and through scattering media, such as skin, fog or potentially even the human skull.

Called synthetic wavelength holography, the new method works by indirectly scattering coherent light onto hidden objects, which then scatters again and travels back to a camera. From there, an algorithm reconstructs the scattered light signal to reveal the hidden objects...

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Astronomers Team up to Create New Method to Understand Galaxy Evolution

S12, a post-starburst galaxy located nearly 500 million light-years away, is on the right. It looks like a jellyfish with a host of stars streaming out of the galaxy on one side.

A husband-and-wife team of astronomers established the star formation history of a post-starburst galaxy using its cluster population. A husband-and-wife team of astronomers at The University of Toledo joined forces for the first time in their scientific careers during the pandemic to develop a new method to look back in time and change the way we understand the history of galaxies.

Until now forging parallel but separate careers while juggling home life and carpooling to cross country meets, Dr. Rupali Chandar, professor of astronomy, and Dr. J.D...

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New approach provides Potential Vaccine and Treatment for Alzheimer’s

A A surface representation of the TAP01 antibody paratope, with the VH and VK domains coloured cyan and green respectively, and the individual complementary determining regions (CDR) highlighted. The conformation and location of the bound AβpE3-14 peptide is shown as a white sticks representation of its covalent structure. B The striking pseudo β-hairpin conformation of the TAP01 bound pE3-14 peptide, which is shown as a covalent sticks representation with stabilising intramolecular hydrogen bonds highlighted. C A detailed view of the TAP01-AβpE3-14 interface, with the bound peptide and interacting antibody residues shown as covalent sticks. TAP01 residues are shown in cyan and green for the VH and VK domains, respectively...
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