Diet Trumps Drugs for Anti-Aging and Good Metabolic Health

A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.

The pre-clinical study by the University of Sydney’s Charles Perkins Centre suggests the makeup of our diet could be more powerful than drugs in keeping conditions like diabetes, stroke and heart disease at bay.

Conducted in mice, the research showed nutrition (including overall calories and macronutrient balance) had a greater impact on ageing and metabolic health than three drugs commonly used to treat diabetes and slow down ageing.

The findings are published in Cell Metabolism.

The research builds on the team’s pioneering work in mice and humans demonstrating the protective role of diet and specific combinations of proteins, fats and carbo...

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Innovative Fabric enables Digital Communication between Wearers, Nearby Devices

Innovative fabric enables digital communication between wearers, nearby devices
Assistant Professor Electrical Engineering and Computer Science Peter Tseng and Amir Hossein Haji Aghajani Memar Doctoral Student. Credit: Steve Zylius/UCI

Imagine your car starting the moment you get in because it recognizes the jacket you’re wearing. Consider the value of a hospital gown that continuously measures and transmits a patient’s vital signs. These are just two applications made possible by a new “body area network”-enabling fabric invented by engineers at the University of California, Irvine.

In a paper published recently in Nature Electronics, researchers in UCI’s Henry Samueli School of Engineering detail how they integrated advanced metamaterials into flexible textiles to create a system capable of battery-free communication between articles of clothing and nearby de...

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Where does Gold come from? New insights into Element Synthesis in the Universe

How are chemical elements produced in our Universe? Where do heavy elements like gold and uranium come from? Using computer simulations, a research team from the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt, together with colleagues from Belgium and Japan, shows that the synthesis of heavy elements is typical for certain black holes with orbiting matter accumulations, so-called accretion disks. The predicted abundance of the formed elements provides insight into which heavy elements need to be studied in future laboratories — such as the Facility for Antiproton and Ion Research (FAIR), which is currently under construction — to unravel the origin of heavy elements. The results are published in the journal Monthly Notices of the Royal Astronomical Society.

All heavy e...

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Using T cells to Target Malignant Brain Tumors

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Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University’s Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

Cellular immunotherapies that specifically target malignant tumors are thought to be a promising approach in cancer medicine. However, a basic requirement for this kind of targeted immunotherapy is to identify target molecules that are found exclusively on the tumor cells and are recognized by the immune system.

Malignant gliomas are incurable brain tumors that spread in the brain and cannot be completely removed by surgery...

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