A chromosome pulled from the flowers of Arabidopsis thaliana (green and white) unspools to reveal DNA (blue) coiled around packaging-proteins called histones (purple). The direction of epigenetic changes by genetic features begins as the RIM transcription factor (pink) docks on a corresponding DNA sequence (pink). Once docked, the RIM transcription factor directs methylation machinery to tack methyl groups (orange) onto specific nearby cytosines (orange).
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Credit: Salk Institute

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in each cell...

As this month’s string of powerful X-class solar flares sparked brilliant auroras that lit up skies across an unusually wide swath of the globe—from northern Europe to Florida—researchers at NJIT’s Center for Solar-Terrestrial Research (CSTR) captured a less visible, but crucial, record of the storm’s impact on Earth’s upper atmosphere.

Recent measurements recorded by NJIT’s new network of radio telescopes show how a rare sequence of intense flares from Nov. 9–14, including an X5.1 event marking 2025’s strongest flare so far, jolted the ionosphere—the plasma-filled atmospheric layer essential for radio signals, GPS accuracy and satellite orbits.

The flares triggered R3 (strong) radio blackouts across Africa and Europe, with several coronal ...

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer. Until now, all available treatments, including immunotherapy—which involves strengthening the immune system to fight cancer—have proved disappointing. CAR-T cells are genetically modified immune cells manufactured in the laboratory and designed to identify and destroy cancer cells.

By targeting a protein present in the tumor environment, a team from the University of Geneva (UNIGE) and the Geneva University Hospital (HUG) has developed CAR-T cells capable of destroying glioblastoma cells. Their efficacy in an animal model of the disease paves the way for clinical trials in humans.

The results are published in the Journal for ImmunoTherapy of Cancer.

Glioblasto...

Soon, researchers may be able to create movies of their favorite protein or virus better and faster than ever before. Researchers at the Department of Energy’s SLAC National Accelerator Laboratory have pioneered a new machine learning method—called X-RAI (X-Ray single particle imaging with Amortized Inference)—that can “look” at millions of X-ray laser-generated images and create a three-dimensional reconstruction of the target particle. The team recently reported their findings in Nature Communications.

X-RAI’s ability to sort through a massive number of images and learn as it goes could unlock limits in data-gathering, allowing researchers to see molecules up close—and perhaps even on the move...