Exposure to Pollutants, Increased Free-radical Damage speeds up Aging

blooming rose, dying rose
A new study by WVU School of Medicine researcher Eric Kelley suggests that unrepaired DNA damage can increase the speed of aging. Kelley and his colleagues genetically modified mice to remove a crucial DNA-repair protein from some of their stem cells. Without this protein, the mice were unable to fix damaged DNA accrued in their immune cells. By the time the genetically modified mice were 5 months old, they resembled a regular two-year-old mouse. For context, a two-year-old mouse is similar in age to an 80-year-old human. (WVU Illustration/Aira Burkhart)

A new study suggests that unrepaired DNA damage can increase the speed of aging. Every day, our bodies face a bombardment of UV rays, ozone, cigarette smoke, industrial chemicals and other hazards.

This exposure can lead to free-rad...

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A Tiny Device Incorporates a compound made from Starch and Baking Soda to Harvest Energy from Movement

The triboelectric nanogenerator (above) is made using a MOF fabricated with cyclodextrin (circular molecule).
DGIST

Scientists have used a compound made from a starch derivative and baking soda to help convert mechanical to electrical energy. The approach, developed by scientists at Daegu Gyeongbuk Institute of Technology (DGIST), with colleagues in Korea and India, is cost-effective and biocompatible, and can help charge low-energy electronics like calculators and watches. The details were published in the journal Advanced Functional Materials.

“Triboelectric nanogenerators harvest mechanical energy and convert it into an electric current,” explains DGIST robotics engineer Hoe Joon Kim...

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‘Pack Ice’ Tectonics reveal Venus’ Geological Secrets

Venus
An oblique radar view of the largest block in the Venus lowlands identified by Byrne et al. Complex belts of tectonic structures bound the block, but the interior is much less deformed, hosting lava flows and a handful of impact craters. Image: Paul Byrne, based on original NASA/JPL imagery.

A new analysis of Venus’ surface shows evidence of tectonic motion in the form of crustal blocks that have jostled against each other like broken chunks of pack ice. The movement of these blocks could indicate that Venus is still geologically active and give scientists insight into both exoplanet tectonics and the earliest tectonic activity on Earth.

“We’ve identified a previously unrecognized pattern of tectonic deformation on Venus, one that is driven by interior motion just like on Earth,” sa...

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There’s more to Genes than DNA: How Mum and Dad add something Extra, just for you

Embryos
A normal 4-day-old mouse embryo (L) and an embryo of the same age that has been manipulated to contain maternal chromosomes only (parthenogenote). At this stage, the embryos (blastocysts) appear similar, but the parthenogenote will soon die, underscoring the importance of inheriting imprinted genes from both parents. Different cell types are stained green or red. Credit: Dr Maki Asami.

Biologists at the Universities of Bath and Vienna have discovered 71 new ‘imprinted’ genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics — an area of science that describes how genes are switched on (and off) in different cells, at different stages in development and adulthood.

To understand the importance of imprinted genes to inherit...

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