Microgel Coating gives Donor Cells a Boost in Reversing Pulmonary Fibrosis

Gel-coated (red) mesenchymal stromal cells (yellow) can degrade collagen (green) over a distance in the presence of tumor necrosis factor-alpha. (Image: Jae-Won Shin and Sing-Wan Wong/UIC)

Single cell encapsulation in gel can optimize cell-based therapy. Researchers at the University of Illinois Chicago have shown that even after lung tissue has been damaged, it may be possible to reverse fibrosis and promote tissue repair through treatment with microgel-coated mesenchymal stromal cells.

Pulmonary fibrosis is a chronic disease caused by environmental toxins, medications or medical conditions like pneumonia and rheumatoid arthritis...

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Researchers Create Self-Sustaining, Intelligent, Electronic Microsystems from Green Material

electronic microsystem
A UMass Amherst research team has developed an electronic microsystem made from protein nanowires, a “green” electronic material that is renewably produced from microbes without producing “e-waste.”

A research team from the University of Massachusetts Amherst has created an electronic microsystem that can intelligently respond to information inputs without any external energy input, much like a self-autonomous living organism. The microsystem is constructed from a novel type of electronics that can process ultralow electronic signals and incorporates a device that can generate electricity “out of thin air” from the ambient environment.

The groundbreaking research was published June 7 in the journal Nature Communications.

Jun Yao, an assistant professor in the electrical and compu...

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Cosmic Cartographers Map Nearby Universe revealing the Diversity of Star-Forming Galaxies

Credit: ALMA (ESO/NAOJ/NRAO)/PHANGS, S. Dagnello (NRAO)

Study reveals that the makeup and life cycle of star-forming clouds is dependent on location. A team of astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA) has completed the first census of molecular clouds in the nearby Universe, revealing that contrary to previous scientific opinion, these stellar nurseries do not all look and act the same. In fact, they’re as diverse as the people, homes, neighborhoods, and regions that make up our own world.

Stars are formed out of clouds of dust and gas called molecular clouds, or stellar nurseries. Each stellar nursery in the Universe can form thousands or even tens of thousands of new stars during its lifetime...

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Researchers identify a Molecule Critical to Functional Brain Rejuvenation

diagram showing the impact of TET1 in young and old mice
In young adult mice (left), TET1 is active in oligodendroglial cells especially after injury and this leads to new myelin formation and healthy brain function. In old mice (right), the age-related decline of TET1 levels impairs the ability of oligodendroglial cells to form functional new myelin. The authors are currently investigating whether increasing TET1 levels in older mice could rejuvenate the oligodendroglial cells and restore their regenerative functions.

The discovery could have important implications for the health of aging brains and development of therapies for neurodegenerative diseases. Recent studies suggest that new brain cells are being formed every day in response to injury, physical exercise, and mental stimulation...

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