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    Gene Therapy durably Reverse Congenital Deafness in mice

    February 24, 2019, Categories  Biology/Biotechnology, Health/Medical

    The left panel is a schematic representation of the human ear. Sound waves are collected by the outer ear made up of the pinna and ear canal. The middle ear, composed of the eardrum and ossicles, transmits sound waves to the inner ear, which features the cochlea – the hearing organ responsible for transmitting auditory messages to the central nervous system. The right panel shows an immunofluorescence image of the auditory sensory epithelium within an injected cochlea. The inner hair cells have been stained for otoferlin in green. Otoferlin is detected in almost all of these cells. The inset is a high magnification area showing an inner hair cell that has not been transduced.
    Credit: © Institut Pasteur

    In collaboration with the universities of Miami, Columbia and San Francisco, scient...

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