Congestive heart failure (CHF) after acute myocardial infarction. Credit: Image courtesy of Osaka University
The onset of cardiac failure after acute myocardial infarction (AMI) is a serious problem throughout the world. Researchers at Osaka University clarified cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.
If the onset of cardiac failure in the chronic phase can be inhibited by this group’s research results that will not only improve patients’ quality of life, but also reduce high medical costs of cardiac failure treatment as a whole.
AMI generates me...
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