adaptor protein tagged posts

A New Player Revealed in Nerve Growth Process

The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity

The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity.

A protein previously known for its role in kidney function, adaptor protein CD2AP, also plays a significant role in the nervous system, and is associated with a type of neural growth known as collateral sprouting. CD2AP orchestrates a complex arrangement of other proteins that controls the branching of nerve axons, the tendrils reaching out from the nerve cell to connect to other nerve cells, skin and organs. This nerve growth occurs in uninjured nerve cells as they extend their reach and create new connections.

Harrison said. “There are a whole bunch of proteins that it could bring together, but it only brings together the correct proteins to create the correct response...

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