The vaccine targets tau proteins (pictured under the microscope) which form tangles in the brain, blocking supplies of vital nutrients to cells, which then die. This triggers the memory loss associated with the disease
In an unprecedented study, active vaccination in humans has resulted in a favorable immune response in 29 out of the 30 patients with only minor side effects. So far, many of the antibody drugs proposed to treat Alzheimer’s disease target only the amyloid plaques. Despite the latest clinical trial that is hailed as our best chance in the quest for treating AD, all later phase trials have failed with many causing severe side effects in the patients, such as abnormal accumulation of fluid and inflammation in the brain...
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