Experiments by a team of NIH-funded scientists suggests a potential method for halting the expansion of certain brain tumors. Credit: Image courtesy of Michelle Monje, M.D., Ph.D., Stanford University
The growth of certain aggressive brain tumors can be halted by cutting off their access to a signaling molecule produced by the brain’s nerve cells, according to a new study by researchers at the Stanford University School of Medicine. When the signaling molecule neuroligin-3 was absent, or when its signal was interrupted with medication, human cancers called high-grade gliomas could not spread in the brains of mice, the researchers found.
“We thought that when we put glioma cells into a mouse brain that was neuroligin-3 deficient, that might decrease tumor growth to some measurable extent...
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