aging brain tagged posts

This nasal spray rewinds the aging brain, restoring memory and reversing inflammation in preclinical models

In Shetty’s lab, researchers develop an innovative nasal spray targeting brain aging.

Credit: Texas A&M University Division of Marketing and Communications

Picture this: your brain is a high-performance engine. Over decades, it doesn’t just wear down, it also starts to run hot. Tiny “fires” of inflammation smolder deep within the brain’s memory center, creating a persistent brain fog that makes it harder to think, form new memories or even adapt to new environments, all the while increasing the risk to disorders like Alzheimer’s disease.

Scientists call this slow burn “neuroinflammaging,” and for decades it was thought to be the inevitable price of growing older. Until now.

A landmark study by researchers at Texas A&M University Naresh K...

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Scientists discover Anti-Inflammatory molecules that Decline in the Aging Brain

The brain is comprised of lipids or fats, but the role of these molecules in health and disease remains unknown. The newly identified class of lipids, called SGDGs, decrease with aging, which suggests they may play a role in brain aging.
Credit: Salk Institute

The molecules, called SGDGs, may lead to new ways to treat age-related neurological diseases. Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process — a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

The research, published in Nature Chemical Biology on...

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The Aging Brain Benefits from Distraction

Increased Activation in Control Regions in Older Adults Tested at a Peak Time of Day.

Increased Activation in Control Regions in Older Adults Tested at a Peak Time of Day.

As you age, you may find it more difficult to focus on certain tasks. But while distractions can be frustrating, they may not be as bad as we think. Researchers at the University of Toronto and Harvard University suggest that there may be some benefits to reduced focus, especially >50yo. Using behavioral studies and neuroimaging, they discuss how being easily distracted can help adults with, eg. problem solving and learning new information.

“Different types of tasks benefit from a more broad focus of attention, and this is usually seen in tasks that involve thinking creatively or using information that was previously irrelevant,” says Tarek Amer, Ph.D.

When people have high cognitive control, they are abl...

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Nonagenarian athlete: Researchers Study Olga Kotelko’s Brain

University of Illinois Beckman Institute postdoctoral researcher Agnieszka Burzynska and her colleagues analyzed the brain and cognition of Olga Kotelko, a 93-year-old track-and-field athlete. Burzynska is now a professor at Colorado State University. Credit: L. Brian Stauffer

University of Illinois Beckman Institute postdoctoral researcher Agnieszka Burzynska and her colleagues analyzed the brain and cognition of Olga Kotelko, a 93-year-old track-and-field athlete. Burzynska is now a professor at Colorado State University. Credit: L. Brian Stauffer

1st glimpse of potential effects of Exercise on the brains and cognitive abilities of the ‘oldest old.’ In the summer of 2012, Olga Kotelko, a 93-year-old Canadian track-and-field athlete with more than 30 world records in her age group, submitted to an in-depth analysis of her brain.

A retired teacher and mother of two, Kotelko started her athletic career late in life: slow-pitch softball at age 65, and at 77 switched to track-and-field events...

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