alcohol tagged posts

A Cleveland Clinic research team studying alcohol and the brain discovered a new way that alcohol abuse can cause brain dysfunction and damage: through immune cells called microglia. The research also identified a potential new treatment target.

The team showed that in a brain affected by alcohol, microglia tear down the extracellular matrix (ECM), the scaffold that surrounds our neurons. The ECM physically holds our brain cells together and allows them to work properly. When it’s disrupted, our neurons can’t communicate as effectively. Severe ECM disruption can affect our ability to move, think and even remain alert.

The research, published in Immunity, is new, fundamental knowledge that already guides the research team to explore new ways to p...

Imagine being able to measure your blood sugar levels, know if you’ve had too much to drink, and track your muscle fatigue during a workout, all in one small device worn on your skin. Engineers at the University of California San Diego have developed a prototype of such a wearable that can continuously monitor several health stats — glucose, alcohol, and lactate levels — simultaneously in real-time.

The device is about the size of a stack of six quarters. It is applied to the skin through a Velcro-like patch of microneedles, that are each about one-fifth the width of a human hair...

Study contradicts perception that drinking is ‘cardioprotective’
A single glass of wine can quickly – significantly – raise the drinker’s risk for atrial fibrillation, according to new research by UC San Francisco.

The study provides the first evidence that alcohol consumption substantially increases the chance of the heart rhythm condition occurring within a few hours. The findings might run counter to a prevailing perception that alcohol can be “cardioprotective,” say the authors, suggesting that reducing or avoiding alcohol might help mitigate harmful effects.

The paper is published August 30, 2021 in Annals of Internal Medicine.

“Contrary to a common belief that atrial fibrillation is associated with heavy alcohol consumption, it appears that even one alcohol drink may be ...

Booze on the brain
Studying fruit flies, researchers at Brown University found that alcohol hijacks a conserved memory pathway in the brain, forming the cravings that fuel addiction. The pink areas are the fly’s memory centers and the green dots are where the first molecular signaling “domino” Notch has been activated.
Kaun Lab/Brown University

Researchers have found that alcohol hijacks a conserved memory pathway in the brain and changes which versions of genes are made, forming the cravings that fuel addiction. One of the many challenges with battling alcohol addiction and other substance abuse disorders is the risk of relapse, even after progress toward recovery...