Mouse (left) and human (right) alveolar progenitor cells grow into large lung organoids in culture, and make multiple types of epithelial cells including gas exchange type 1 cells (red) and surfactant-producing type 2 cells (green). Credit: The lab of Ed Morrisey, Perelman School of Medicine, University of Pennsylvania.
Implications for new approaches to repair damaged lung disease. Researchers have identified a lung stem cell that repairs the organ’s gas exchange compartment, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. They isolated and characterized these progenitor cells from mouse and human lungs and demonstrated they are essential to repairing lung tissue damaged by severe influenza and other respiratory ailments.
The development of...
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