bioimaging tagged posts

A schematic of development of Gamillus. Gene of the fluorescent protein was cloned from tentacles of flower hat jellyfish, and was engineered to improve the monomeric property and the brightness. Credit: Kamo Aquarium and Osaka University (The flower hat jellyfish was provided by Mr. Kamoizumi in Kamo Aquarium, Yamagata, Japan.)

Osaka University researchers develop new green fluorescent protein that can withstand low pH environment for imaging of acidic organelles. Visualizing cellular components and processes at the molecular level is important for understanding the basis of any biological activity. Fluorescent proteins (FPs) are one of the most useful tools for investigating intracellular molecular dynamics.

However, FPs have usage limitations for imaging in low pH environments, such as ...

An artist’s rendering shows the layers of a new, onion-like nanoparticle whose specially crafted layers enable it to efficiently convert invisible near-infrared light to higher energy blue and UV light. Credit: Kaiheng Wei (Davidwei_loga@foxmail.com)

A dye-coated surface is 1 of 3 specially crafted layers that help the particle emit light ideal for bioimaging, solar energy harvesting and light-based security techniques. The particle’s innovation lies in its layers: a coating of organic dye, a neodymium-containing shell, and a core that incorporates ytterbium and thulium...