
This graphic illustrates how eating within a 10-hour window protects mice from metabolic disease regardless of whether their bodies have functional circadian clocks.
Credit: Salk Institute
Periods of fasting can protect against obesity and diabetes. Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic diseases by having their daily access to food restricted to a 10-hour window.
The work, which appeared in the journal Cell Metabolism on August 30, 2018, suggests that the health problems associated with disruptions to animals’ 24-hour rhythms of activity and rest – which in humans is linked to eating for most of the day or doing shift work – can be corrected by eat...
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