caffeine tagged posts

Caffeine may flip an ancient cellular switch linked to slower aging

Caffeine May Slow Cellular Aging
Caffeine could have surprising effects on cellular aging by activating AMPK, a system that helps cells manage energy and stress. Credit: Shutterstock

Caffeine may help cells age more slowly by switching on a powerful energy and stress-response system. Scientists found that caffeine activates an ancient cellular energy system involved in stress resistance, DNA repair, and growth. The discovery could help explain caffeine’s links to healthier aging and may point toward new ways to target the same pathway.

Your morning coffee may be doing more than helping you wake up.

Research from Queen Mary University of London suggests that caffeine can activate an ancient cellular energy system involved in growth, stress resistance, and DNA repair...

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Espresso can Prevent Alzheimer’s Protein Clumping in Lab Tests

A cup of espresso.
In an in vitro study, espresso and certain compounds found within it could prevent tau aggregation, which is associated with Alzheimer’s disease.
Alessio Orru/Shutterstock.com

Whether enjoyed on its own or mixed into a latte, Americano or even a martini, espresso provides an ultra-concentrated jolt of caffeine to coffee lovers. But it might do more than just wake you up. Research now published in ACS’ Journal of Agricultural and Food Chemistry shows that, in preliminary in vitro laboratory tests, espresso compounds can inhibit tau protein aggregation — a process that is believed to be involved in the onset of Alzheimer’s disease.

Roughly half of all Americans drink coffee every day, and espresso is a popular way to consume it...

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Molecular Component of Caffeine may play a Role in Gut Health

Molecular component of caffeine may play a role in gut health
Credit: Immunity (2023). DOI: 10.1016/j.immuni.2023.02.018

Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators better understand gut health and the development of conditions such as inflammatory bowel disease.

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

A new study by investigators from Brigham and Women’s Hospital explores exactly what lead...

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Coffee lovers, rejoice! Drinking more coffee associated with Decreased Heart Failure Risk

Image result for Coffee lovers, rejoice! Drinking more coffee associated with Decreased Heart Failure Risk

Circulation: Heart Failure Journal Report..Dietary information from 3 large, well-known heart disease studies suggests drinking one or more cups of caffeinated coffee may reduce heart failure risk, according to research published today in Circulation: Heart Failure, an American Heart Association journal.

Coronary artery disease, heart failure and stroke are among the top causes of death from heart disease in the U.S. “While smoking, age and high blood pressure are among the most well-known heart disease risk factors, unidentified risk factors for heart disease remain,” according to David P. Kao, M.D...

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