cancer tagged posts

Wear and forget: An Ultrasoft Material for On Skin Health Devices

. Leakage-resistant property.
Conceptual illustration of conventional nonporous (A) and multifunctional porous (B) EGaIn composites upon compression. Here, porous structures can provide damping effect to substantially reduce stresses induced on liquid metal conductive pathways (see details in fig. S5), therefore endowing leakage-resistant property. In addition, antimicrobial additive can offer antibacterial and antiviral property. (C) Chemical structure of the antimicrobial additive, ε-PL, modified with BEHS for uniform dispersion in solvents. (D) Schematic of the EGaIn particle made by tip sonication of bulk EGaIn. (E) 3D tomography image of porous composites before sintering, showing EGaIn particle (yellow) distributions in elastomers (pink). Scale bar, 100 μm. (F) Photographs of compr...
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Treating Tough Tumors by exploiting their Iron ‘Addiction’

A microscopic image of KRAS-driven lung cancer (purple) in a mouse model. Researchers found that KRAS-driven tumors have higher levels of ferrous iron, which correlates with shorter survival times. Image by National Cancer Institute, National Institutes of Health

Researchers at the University of California, San Francisco, have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about 1 in 4 cancer deaths.

Taking advantage of what they discovered to be the cancer cells’ appetite for a reactive form of iron, the researchers tweaked an anticancer drug to operate only in these iron-rich cells, leaving other cells to function normally...

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30-60 mins of Weekly Muscle Strengthening Activity linked to 10-20% Lower Death Risk

Credit: Unsplash/CC0 Public Domain

Between 30 and 60 minutes of muscle strengthening activity every week is linked to a 10-20% lower risk of death from all causes, and from cardiovascular disease, diabetes, and cancer, in particular, finds a pooled data analysis of the available evidence, published online in the British Journal of Sports Medicine.

The findings are independent of aerobic exercise. But the analysis points to a J-shaped curve for most outcomes, with no conclusive evidence that more than an hour a week of muscle strengthening activity reduces the risk further still.

Physical activity guidelines recommend regular muscle strengthening activities for adults, primarily because of the known benefits for skeletal muscle health...

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Free Radicals Linked to Heart Damage caused by Cancer


Photo: Shutterstock.com

In fruit flies, antioxidants reverse tumor-related cardiac dysfunction. A new study in animal models shows that the presence of a cancer tumor alone can lead to cardiac damage, and suggests the culprits are molecules are free radicals interacting with specific cells in the heart.

Tumors in mice and fruit flies led to varying degrees of cardiac dysfunction – particularly a decrease in the heart’s blood-pumping capabilities.

Adding specific types of antioxidants to food consumed by fruit flies with tumors reversed the damage to their hearts – a finding suggesting that harm caused by free radicals was the likely link between cancer and cardiac dysfunction.

“Cancer becomes a systemic disease...

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