cancer tagged posts

Tumors Hijack the Cell Death Pathway to Live

From left: Drs. Yang-Xin Fu, Chuanhui Han, and Zhida Liu
From left: Drs. Yang-Xin Fu, Chuanhui Han, and Zhida Liu

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests. The findings, published in a recent issue of Nature Immunology, could eventually lead to new ways to augment existing treatments to fight this disease.

Researchers have long known that radiation – a mainstay of treatment protocols for many types of cancerous tumors – kills cancer cells in two different ways: The high-energy beams smite some cells directly, and these dead cells leak DNA that triggers a tumor-fighting immune response through proteins known as interferons (IFNs)...

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Experts discover Toolkit to Repair DNA Breaks linked to Aging, Cancer and MND

A human cell showing sites of DNA breaks repaired by TEX246
A human cell showing sites of DNA breaks repaired by TEX246

A new ‘toolkit’ to repair damaged DNA that can lead to ageing, cancer and Motor Neurone Disease (MND) has been discovered by scientists at the Universities of Sheffield and Oxford.

Published in Nature Communications, the research shows that a protein called TEX264, together with other enzymes, is able to recognise and ‘eat’ toxic proteins that can stick to DNA and cause it to become damaged. An accumulation of broken, damaged DNA can cause cellular ageing, cancer and neurological diseases such as MND.

Until now, ways of repairing this sort of DNA damage have been poorly understood, but scientists hope to exploit this novel repair toolkit of proteins to protect us from ageing, cancer and neurological disease.

The fin...

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Proton Therapy Lowers Risk of Side Effects in Cancer compared to Traditional Radiation

Penn researchers have demonstrated that proton therapy reduces the likelihood of adverse affects among cancer patients also being treated with chemotherapy. The study compared proton therapy patients to those receiving traditional photon radiation. SOURCE/PERELMAN SCHOOL OF MEDICINE

Study found protons led to two-thirds reduction in unplanned hospitalizations. Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical...

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Possible link between Sugary Drinks and Cancer

Fig1
Contribution of each beverage type to the total of sugary drinks and artificially sweetened beverage consumption

A study published by The BMJ today reports a possible association between higher consumption of sugary drinks and and an increased risk of cancer. While cautious interpretation is needed, the findings add to a growing body of evidence indicating that limiting sugary drink consumption, together with taxation and marketing restrictions, might contribute to a reduction in cancer cases.

The consumption of sugary drinks has increased worldwide during the last few decades and is convincingly associated with the risk of obesity, which in turn is recognised as a strong risk factor for many cancers. But research on sugary drinks and the risk of cancer is still limited.

So a t...

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