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    Chronic pain is reflected in the folds and grooves of the cerebral cortex

    August 28, 2026, Categories  Health/Medical, Biology/Biotechnology

    Chronic pain is reflected in the folds and grooves of the cerebral cortex
    Surface-based morphometry workflow for ROI-wise cortical surface feature extraction. Surface atlases were mapped to individual surfaces using the spherical registration parameters obtained during surface processing. Surface-based measures (e.g., cortical thickness, sulcal depth) were then extracted for each ROI in native space. Credit: NeuroImage: Clinical (2026). DOI: 10.1016/j.nicl.2026.104023 Created in BioRender. https://BioRender.com/4zyhoc8.

    Persistent pain often has no clear cause. However, studies show measurable differences in the structure and activity of the brains of those affected. This might explain why they experience chronic pain...

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