cognitive decline tagged posts

Daily Consumption of Tea protects the elderly from Cognitive decline

NUS researchers found that regular consumption of tea brewed from tea leaves reduces elderly persons’ risk of cognitive decline

NUS researchers found that regular consumption of tea brewed from tea leaves reduces elderly persons’ risk of cognitive decline

Tea drinking reduces the risk of cognitive impairment in older persons by 50% and as much as 86% for those who are genetically at risk of Alzheimer’s. A cup of tea a day can keep dementia away, and this is especially so for those who are genetically predisposed to the debilitating disease, according to a recent study led by Assistant Professor Feng Lei from the Department of Psychological Medicine at National University of Singapore’s (NUS) Yong Loo Lin School of Medicine.

The longitudinal study involving 957 Chinese seniors aged 55 years or older has found that regular consumption of tea lowers the risk of cognitive decline in the elderly by 50 per cent, while ...

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Pot May Restrict Blood Flow to Brain: study

Pot may restrict blood flow to brain: study

Marijuana appears to hamper blood flow to the brain, which theoretically could affect your memory and ability to reason, a new study suggests.

Marijuana appears to hamper blood flow to the brain, which theoretically could affect your memory and ability to reason, a new study suggests. Brain scans of nearly 1,000 past and present marijuana users revealed abnormally low blood flow throughout their brains, compared with a smaller control group of 92 people who’d never used pot. “The differences were astonishing,” said Dr. Daniel Amen, a psychiatrist and founder of the U.S.-based Amen Clinics. “Virtually every area of the brain we measured was lower in blood flow and activity in the marijuana smokers than in the healthy group.”

Blood flow was lowest in the hippocampus of marijuana users, which...

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Antibody, Aducanumab, reduces harmful brain Amyloid Plaques in Alzheimer’s patients

Biogen Alzheimer's paper Figure 1 | Amyloid plaque reduction with aducanumab: example amyloid PET images at baseline and week 54. Individuals were chosen based on visual impression and SUVR change relative to average one-year response for each treatment group (n = 40, 32, 30 and 32, respectively). Axial slice shows anatomical regions in posterior brain putatively relatedto AD pathology. SUVR, standard uptake value ratio.

Amyloid plaque reduction with aducanumab: example amyloid PET images at baseline and week 54. Axial slice shows anatomical regions in posterior brain putatively related to Alzheimer’s disease pathology

The researchers furthermore demonstrated in an early stage clinical study that, after 1 year of treatment with Aducanumab, cognitive decline could be significantly slowed in antibody-treated patients as opposed to the placebo group. Although the causes of Alzheimer’s disease are still unknown, it is clear that the disease commences with progressive amyloid deposition in the brains of affected persons between 10 to 15 years before the emergence of initial clinical symptoms such as memory loss...

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Lipid-based diets effectively Combat Alzheimer’s disease in mouse model

Researchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Science Publishers

Researchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer’s disease. Credit: Janickova et al, Bentham Science Publishers

Numerous epidemiological studies have revealed profitable effects of dietary intake of especially fish oil on cognitive decline during aging and dementia. One of the invariable pathologies in AD is degeneration of cholinergic synapses in brain cortex and hippocampus. Current pharmacological interventions are limited to a few drugs that alleviate symptoms but do not slow down the underlying disease processes eg inhibitors of cholinesterases, enzymes that degrade the neurotransmitter acetylcholine, or memantine, a modulator of glutamate neurotransmission.

Within the EU-funded project LipiDiDiet (FP7-211696, the...

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