COMPASS tagged posts

AI tool improves prediction of who will respond to cancer immunotherapy drugs

AI tool improves prediction of who will respond to cancer immunotherapy drugs
Fine-tuning strategies based on the pretrained COMPASS model. Credit: Nature Medicine (2026). DOI: 10.1038/s41591-026-04502-7

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others. But these drugs work for only a subset of patients, with few indications why—a knowledge gap that has detrimental effects on patient prognosis, clinical trial recruitment and research that could lead to new therapies.

A new artificial intelligence model called COMPASS, developed by Harvard Medical School researchers and their colleagues, improves prediction of which patients are most likely to respond to ICIs...

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