•H2A.Z and H2BK120ub1 mark nascent chromatin prior to transcription re-start
•H2A-H2B modification and variant landscapes are restored rapidly after replication
•H2AK119ub1 facilitates accurate and timely restoration of H3K27me3 post-replication
In a new study, researchers discovered an unknown mechanism of how cells ‘remember’ their identity when they divide – the cells’ so-called epigenetic memory. As time passes and we get older, many cells need to replenish themselves. They do so by dividing into new cells: Heart cells, skin cells and so on.
But when cells continue to divide and make new cells, they lose some of the information from their mother cell...
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