CRISPR activation tool tagged posts

Gene that drives blood cancer drug resistance uncovered with new CRISPR activation tool

Gene
Credit: Unsplash/CC0 Public Domain

Researchers have uncovered a previously unknown gene that causes resistance to a leading blood cancer drug, as well as several genes that accelerate lymphoma growth, using a powerful new CRISPR activation library.

Traditional CRISPR is a genetic engineering tool that allows scientists to easily delete specific genes in an organism’s DNA and assess their role and importance. It has become a cornerstone technology in cancer research.

A newer frontier is CRISPR activation, a technique that enables the activation of specific genes. It offers valuable insights into the roles of certain genes in cancer and other genetic disorders.

A team of researchers from the Olivia Newton-John Cancer Research Institute (ONJCRI), WEHI and Genentech, a member of t...

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