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    Experimental Drug Reverses Hair Loss and Skin Damage linked to Fatty Diet, shows new study in mice

    July 31, 2018, Categories  Health/Medical, Biology/Biotechnology

    Mechanism of action of lactosylceramide in skin inflammation and restoration by the use of D-PDMP. Feeding a western diet raises the level of oxidized phospholipid which activates Lactosylceramide synthase (GalT-V) to generate lactosylceramide which produces reactive oxygen species-a pro-oxidant environment. Lactosylceramide also reacts with infiltrating neutrophils to activate phospholipase A-2, thus releasing arachidonic acid, eicosanoids and contributing to inflammation. This cycle of events can be broken by the judicious use of D-PDMP/BPD.

    Mechanism of action of lactosylceramide in skin inflammation and restoration by the use of D-PDMP. Feeding a western diet raises the level of oxidized phospholipid which activates Lactosylceramide synthase (GalT-V) to generate lactosylceramide which produces reactive oxygen species-a pro-oxidant environment. Lactosylceramide also reacts with infiltrating neutrophils to activate phospholipase A-2, thus releasing arachidonic acid, eicosanoids and contributing to inflammation. This cycle of events can be broken by the judicious use of D-PDMP/BPD.

    The research advances search for compounds that may someday accelerate wound healing and reverse balding...

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