deliver drugs tagged posts

Scientists develop a new way to Deliver Drugs through the Skin

Scientists develop new way to deliver more drugs through the skin
A prototype patent-pending temporal pressure device developed by the NTU and A*STAR scientists, which can put pressure on the skin, thus creating micropores that allow the drugs to pass through the skin easier. Credit: Nanyang Technological University

Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR) have shown that applying ‘temporal pressure’ to the skin of mice can create a new way to deliver drugs.

In a paper published in Science Advances, the researchers showed that bringing together two magnets so that they pinch and apply pressure to a fold of skin, led to short term changes in the skin barrier and specifically the formation of “micropores” underneath its surface.

In tests, they showed t...

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Personalized Microrobots Swim through Biological Barriers, deliver Drugs to 570Cells

Illustration (top) and scanning electron microscopy image (bottom) of biohybrid bacterial microswimmers, which were fabricated by combining genetically engineered E. coli MG1655 and nanoerythrosomes made from red blood cells. A biotin-streptavidin interaction was used to attach nanoerythrosomes to the bacterial membrane. CREDIT:
Image courtesy of the authors

Tiny biohybrid robots on the micrometer scale can swim through the body and deliver drugs to tumors or provide other cargo-carrying functions. The natural environmental sensing tendencies of bacteria mean they can navigate toward certain chemicals or be remotely controlled using magnetic or sound signals.

To be successful, these tiny biological robots must consist of materials that can pass clearance through the body’s immune res...

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Wireless System can Power Devices inside the Body

MIT researchers have developed technology that could be used to remotely trigger “smart pills” to deliver drugs.

MIT researchers have developed technology that could be used to remotely trigger “smart pills” to deliver drugs.

New technology could enable remote control of drug delivery, sensing, and other medical applications. MIT researchers, working with scientists from Brigham and Women’s Hospital, have developed a new way to power and communicate with devices implanted deep within the human body. Such devices could be used to deliver drugs, monitor conditions inside the body, or treat disease by stimulating the brain with electricity or light.

The implants are powered by radio frequency waves, which can safely pass through human tissues. In tests in animals, the researchers showed that the waves can power devices located 10 centimeters deep in tissue, from a distance of 1 meter.

“Even though t...

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