dementia tagged posts

Forgetting the name of a loved one may be one of the first signs people notice of dementia, but it’s rarely the first warning sign your brain gives. Changes in the brain that lead to neurodegenerative diseases like Alzheimer’s and dementia start showing up decades before symptoms arrive, and the chemicals at work inside the body can often tip us off to these changes well ahead of time.

A recent study found that a blood protein called GDF15, which is released when cells are under stress, could serve as one of the earliest warning signs of dementia. After tracking more than half a million people for 15–25 years, researchers discovered that those with higher GDF15 levels before age 55 were significantly more likely to develop dementia later in life...

A blood test, combined with an ultrathin material derived from graphite, could significantly advance efforts to detect Alzheimer’s disease at its very earliest stage, even before symptoms appear.

Alzheimer’s disease is the most common form of dementia. For millions of Europeans—and the health services that care for them—it is a ticking time bomb, with still no cure. But EU researchers are developing a simple tool to enable much earlier detection, potentially decades before symptoms appear.

Early detection matters because treatment is most effective when started as soon as possible. This gives people a better chance to slow the progression of the disease and plan for the future...

A new study reveals that fragmented sleep causes cellular damage to the brain’s blood vessels, providing further evidence to suggest that sleep disruption predisposes the brain to dementia.

The research, published in the journal Brain, is the first to offer cellular and molecular evidence that sleep disruption directly causes damage to brain blood vessels and blood flow.

“We found that individuals who had more fragmented sleep, such as sleeping restlessly and waking up a lot at night, had a change in their balance of pericytes—a brain blood vessel cell that plays an important role in regulating brain blood flow and the entry and exit of substances between the blood and the brain,” said Andrew Lim, principal investigator of the study and a sleep neurologist and scientist at Sunny...

Get on your bike and ride, a new study recommends.
Biking regularly for transportation appears to lower risk of dementia by 19% and Alzheimer’s by 22%, according to results published June 9 in JAMA Network Open.

The results also suggest that cycling might even help increase the size of a brain region important for memory, researchers noted.

“Cycling is a moderate- to high-intensity workout, and also requires balance,” said Dr. Liron Sinvani, director of geriatric services at Northwell Health in Manhasset, N.Y., who reviewed the findings. “It requires more complex brain functions than walking, which is why maybe it was a better reducer of dementia risk.”

“It’s not about just doing exercise and making that part of your...