How bioelectricity strengthens the innate immune response (Credit: Jean-Francois Pare/Tufts University)
Drugs already approved for other uses in people help frogs survive deadly E. coli by changing their cells’ electrical charge. Changing the natural electrical signaling that exists in cells outside the nervous system can improve resistance to life-threatening bacterial infections, according to new research from Tufts University biologists. The researchers found that administering drugs, including those already used in humans for other purposes, to make the cell interior more negatively charged strengthens tadpoles’innate immune response to E. coli infection and injury...
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