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    DNA-activated bone-ECM-mimicking surface coating tagged posts

    Packaged DNA: New Method to Promote Bone Growth

    February 14, 2023, Categories  Health/Medical, Biology/Biotechnology

    Researchers develop new method to promote bone growth
    Schematic illustration of the DNA-activated bone-ECM-mimicking surface coating. The lipid components OO4/DOPE were formulated to cationic liposomes. The cationic liposomes were assembled with DNA encoding either of the reporter gene green fluorescent protein (GFP) or the therapeutic gene BMP-2, to LPX. LPX were assembled into DNA-activated surface coatings as tool for in situ transfection using the LbL technique. Credit: Advanced Healthcare Materials (2022). DOI: 10.1002/adhm.202201978

    DNA can help to stimulate bone healing in a localised and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery...

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