DNA computers tagged posts

Computer scientists Create Reprogrammable Molecular Computing System


Artist’s representation of a DNA computing system.
Credit: Caltech

Computer design meets potions class: A little of vial 1 and a little of vial 2 yield six-bit computations encoded in DNA. Computer scientists at Caltech have designed DNA molecules that can carry out reprogrammable computations, for the first time creating so-called algorithmic self-assembly in which the same “hardware” can be configured to run different “software.”

In a paper published in Nature on Feb XX, a team headed by Caltech’s Erik Winfree (PhD ’98), professor of computer science, computation and neural systems, and bioengineering, showed how the DNA computations could execute six-bit algorithms that perform simple tasks...

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Building Computers from DNA?

Graphical abstract: Reversible DNA i-motif to hairpin switching induced by copper(ii) cations

i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used changes in pH to fold the DNA. Herein we describe how copper(II) cations can alter the conformation of i-motif DNA into an alternative hairpin structure which is reversible by chelation with EDTA

Scientists can now ‘switch’ the structure of DNA using copper salts and EDTA. Ethylenediaminetetraacetic acid is an agent commonly found in shampoo and other household products. The applications for this discovery include nanotechnology – where DNA is used to make tiny machines, and in DNA-based computing – where computers are built from DNA rather than silicon...

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