DNA enhancers tagged posts

Imaging in Living Cells reveals how ‘Junk DNA’ Switches on a Gene

Using an imaging technique developed at Princeton, researchers captured the moment when a segment of DNA -- from genetic material that was once thought to be useless junk -- turns on a target gene. Here, a time series of images reveals how a DNA segment known as an enhancer can turn on, or activate, its target gene. The enhancer (blue) must come in close proximity to the gene (green) to turn on gene activity (pink). Credit: Hongtao Chen, Princeton University

Using an imaging technique developed at Princeton, researchers captured the moment when a segment of DNA — from genetic material that was once thought to be useless junk — turns on a target gene. Here, a time series of images reveals how a DNA segment known as an enhancer can turn on, or activate, its target gene. The enhancer (blue) must come in close proximity to the gene (green) to turn on gene activity (pink).
Credit: Hongtao Chen, Princeton University

Video shows DNA enhancers finding and activating a target gene in a living cell. Researchers have captured video showing how pieces of DNA once thought to be useless can act as on-off switches for genes. These pieces of DNA are part of over 90% of the genetic material that are not genes...

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