Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. JRSM Open, 2017; 8 (5): 205427041769429 DOI: 10.1177/2054270417694291
There is no significant difference between zinc acetate lozenges and zinc gluconate lozenges regarding their efficacy in shortening the duration of common colds according to a meta-analysis in Journal of the Royal Society of Medicine Open. 7 randomized trials found that the duration of colds was shortened on average by 33%.
Zinc lozenges appear to influence the common cold through the release of free zinc ions into the oro-pharyngeal region. However, zinc ions can bind tightly to various chemical complexes in such a way that little or no free zinc ions are released...
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