ErbB receptors tagged posts

Synthetic Biology used to Target Cancer Cells while Sparing Healthy Tissue

(Top) some types of cancers are caused by mutated or overexpressed cell surface proteins that signal to the nucleus (green pathway) to drive uncontrolled growth and survival. (Bottom) Using an approach called RASER, the cancer-causing signals are redirected away from cell growth and survival and toward programmed cell death (orange pathway).
Michael Lin and Stuart Jantzen

Synthetic proteins engineered to recognize overly active biological pathways can kill cancer cells while sparing their healthy peers, according to a study by researchers at the Stanford University School of Medicine...

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