The hippocampus is a region of the brain largely responsible for memory formation. Credit: Salk Institute
A combined team of researchers have found 3 types of repressive regulations in the hippocampus of mice that impact memory retention. To gain a better idea of how genes are involved in the memory making process, the researchers trained several mice to fear being put into a cage, by administering electric shocks. They then killed the mice after differing amounts of time had passed (five minutes, ten minutes , a half hour and at four hours) and performed RNA sequencing and ribosome profiling on the hippocampus. Doing so led to the identification of 104 genes that deviated from a control group, each with either translation or transcription differences.
In studying the data, the researchers...
Read More
Recent Comments