
UT Southwestern researchers have helped reveal the molecular structure of alpha Klotho (a-Klotho), the so-called “anti-aging” protein
Researchers reveal the molecular structure of the so-called ‘anti-aging’ protein alpha Klotho (a-Klotho) and how it transmits a hormonal signal that controls a variety of biologic processes. Studies at UTSW two decades ago by Dr. Makoto Kuro-o, Professor of Pathology, demonstrated that mice lacking either a-Klotho or the hormone FGF23 suffered from premature and multiple organ failure as well as other conditions, including early onset cardiovascular disease, cancer, and cognitive decline...
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