for G-protein-coupled receptors tagged posts

Gut Bacteria that ‘Talk’ to Human Cells may lead to new Treatments

1. Combined analysis of protein and transcript expression of GPCRs in the gastrointestinal tract. Links between GPCR, N-acyl amide, bacterial genus and the site where these co-occur in the gastrointestinal tract (coloured) are shown. 2. Proposed two-step biosynthesis of N-acyl serinol using the two domains encoded by the hm-NAS N-acyl serinol synthase gene.

1. Combined analysis of protein and transcript expression of GPCRs in the gastrointestinal tract. Links between GPCR, N-acyl amide, bacterial genus and the site where these co-occur in the gastrointestinal tract (coloured) are shown.
2. Proposed two-step biosynthesis of N-acyl serinol using the two domains encoded by the hm-NAS N-acyl serinol synthase gene.

Scientists developed a method to genetically engineer gut bacteria to produce molecules that have the potential to treat certain disorders by altering human metabolism. We have a symbiotic relationship with the trillions of bacteria that live in our bodies – they help us, we help them. It turns out that they even speak the same language based on molecules called ligands...

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