glucocorticoid-rhythm disruption tagged posts

Stress hormone timing creates a different kind of obesity, study suggests

histology of liver tissue
Liver tissue from mice after 60 days of treatment. From left to right: control, glucocorticoid-rhythm flattening, and high-fat diet. The top row shows H&E-stained liver tissue, while red staining in the bottom row marks fat in the liver. Mice with flattened glucocorticoid rhythms on a standard diet displayed minimal liver fat compared with mice fed a high-fat diet, despite similar obesity. Scale bar, 100 µm. Credit: Teruel Lab

Obesity caused by disrupted stress-hormone rhythms is metabolically very different from obesity caused by a high-fat diet, according to a new preclinical study by Weill Cornell Medicine investigators...

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