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    Using Holographic Endoscopes to Observe Distant Objects

    April 3, 2021, Categories  Health/Medical, Biology/Biotechnology

    A sequence of holograms displayed by a digital micromirror device spatially shapes the wavefronts coupled into a multimode optical fiber in such a way that a far-field focus scans the distal field of view. CREDIT: Tomas Cizmar
    A sequence of holograms displayed by a digital micromirror device spatially shapes the wavefronts coupled into a multimode optical fiber in such a way that a far-field focus scans the distal field of view. CREDIT: Tomas Cizmar

    Endoscopes made of single-hair thin optical fibers can reconstruct images of macroscopic objects at larger imaging distances. Scientists are developing tools to observe the biological machinery in in vivo animal models to be able to understand and better treat severe brain diseases like Alzheimer’s disease and many other conditions. Holographic endoscopes attracted researchers’ interest because of their potential to conduct minimally invasive observations inside the human body.

    These tools can shed light on the biological processes occurring at the macromolecu...

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