host defense peptides tagged posts

The South Indian frog Hydrophylax bahuvistara is shown. Credit: Sanil George + Jessica Shartouny

Mining host defense peptides found in skin mucus. A component of the skin mucus secreted by South Indian frogs can kill the H1 variety of influenza viruses, researchers from Emory Vaccine Center and the Rajiv Gandhi Center for Biotechnology in India have discovered. Frogs’ skins were known to secrete “host defense peptides” that defend them against bacteria. The finding suggests that the peptides represent a resource for antiviral drug discovery as well.

Anti-flu peptides could become handy when vaccines are unavailable, in the case of a new pandemic strain, or when circulating strains become resistant to current drugs, says Joshy Jacob, PhD, associate professor of microbiology and immunology a...